摘要：

Trypsin is an ancient protease best known as a digestive enzyme in animals, and traditionally believed to be absent in plants and protists. A dinoflagellate bloom study we conducted in the Changjiang Estuary led us to question that notion. We found trypsin genes in diatoms were highly expressed before the dinoflagellate bloom and when environmental phosphorus concentration was declining. We then found that trypsin genes occur widely in different phyla of phytoplankton and throughout the global ocean. Our analysis further indicates that the expression of trypsin genes in diatoms is correlated with N and P nutrient conditions in the ocean. Furthermore, using CRISPR/Cas9 genome editing technology, we demonstrate that one of the trypsin genes in the model diatom Phaeodactylum tricornutum is a coordinate regulator of N and P nutrient homeostasis. This work advances our knowledge on the distribution of trypsin in the tree of life and reveals a new function of trypsin in phytoplankton, underscoring the need for further inquiries into evolutionary implications and ecological roles of trypsins in different groups of phytoplankton.  

个人简介：

康涅狄格大学（美国）/我校教授，美国科学促进会会士（AAAS Fellow），康涅狄格州科学院院士，湖沼与海洋科学学会会士（ASLO Fellow），藻类学会选举委员会主任。历任 Journal of Phycology，Frontiers in Microbiology等重要期刊的副主编或编委，在Science, PNAS等顶尖期刊发表学术论文200余篇，是国际上具有开拓性的海洋生态学领域知名学者。

腾讯会议：https://meeting.tencent.com/dm/Zpsn8C4TOnbn

会议ID：307-956-214